Biblia Koshodou no Jiken Techou is a mystery series where Shinokawa Shioriko, a young owner of a bookstore in Kamakura, unravels mysteries of ancient books that are taken there.

The story begins with a young man named Daisuke, who grew up practically without reading books due to a "phobia", bringing the complete (and autographed) works of Natsume Soseki, Japanese writer of the Meiji era, inherited from his grandmother, to the mysterious bookstore. Will the shy and introvert Shioriko solve the mystery of the books?